CCL21 antibody (Middle Region)

Catalog No. ABIN950189

The Rabbit Polyclonal anti-CCL21 antibody is suitable to detect CCL21 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for CCL21 antibody (Middle Region) (ABIN950189)

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL21 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CCL21 Antibody

Binding Specificity: AA 30-60, Middle Region

Specificity: This antibody reacts to CCL21.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 30-60 amino acids from the Central region of human CCL21

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CCL21

Target: CCL21 (Chemokine (C-C Motif) Ligand 21 (CCL21))

Alternative Name: 6CKine / CCL21

Background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq].Synonyms: Beta chemokine Exodus-2, CCL-21, SCYA21, SLC, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21

Molecular Weight: 14646 Da

Gene ID: 6366

NCBI Accession: NP_002980

Pathways: Regulation of Actin Filament Polymerization