ACTN3 antibody (Middle Region)

Catalog No. ABIN950371

This Rabbit Polyclonal antibody specifically detects ACTN3 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for ACTN3 antibody (Middle Region) (ABIN950371)

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACTN3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ACTN3 Antibody

Binding Specificity: AA 408-437, Middle Region

Specificity: This antibody reacts to Alpha-actinin-3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 408-437 amino acids from the Central region of human ACTN3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ACTN3

Target: ACTN3 (Actinin, alpha 3 (ACTN3))

Alternative Name: alpha-Actinin-3 / ACTN3

Background: Alpha-actinin is an actin-binding protein with multiple roles in different cell types. This gene expression is limited to skeletal muscle. It is localized to the Z-disc and analogous dense bodies, where it helps to anchor the myofibrillar actin filaments.Synonyms: Alpha actinin skeletal muscle isoform 3, F-actin cross-linking protein

Gene ID: 89

NCBI Accession: NP_001095

Pathways: Cell-Cell Junction Organization