AGLU antibody (N-Term)

Catalog No. ABIN950380

This Rabbit Polyclonal antibody specifically detects AGLU in WB, EIA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for AGLU antibody (N-Term) (ABIN950380)

Target: AGLU (alpha-Glucosidase (AGLU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGLU antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-AGLU Antibody

Binding Specificity: AA 173-203, N-Term

Specificity: This antibody recognizes Human Alpha-glucosidase (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: conjugated synthetic peptide between 173-203 amino acids from the N-terminal region of Human Alpha-glucosidase Genename: GAA

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for AGLU

Target: AGLU (alpha-Glucosidase (AGLU))

Alternative Name: alpha-Glucosidase

Background: This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Acid maltase, Aglucosidase alfa, GAA, LYAG, Lysosomal alpha-glucosidase

Molecular Weight: 105319 Da

Gene ID: 2548

NCBI Accession: NP_000143

Pathways: Cellular Glucan Metabolic Process