Angiopoietin 1 antibody (C-Term)

Catalog No. ABIN950411

The Rabbit Polyclonal anti-Angiopoietin 1 antibody has been validated for WB and EIA. It is suitable to detect Angiopoietin 1 in samples from Human.

Quick Overview for Angiopoietin 1 antibody (C-Term) (ABIN950411)

Target: Angiopoietin 1 (ANGPT1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Angiopoietin 1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Angiopoietin 1 Antibody

Binding Specificity: AA 378-410, C-Term

Specificity: This antibody reacts to Angiopoietin-1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 378-410 amino acids from the C-terminal region of human ANGPT1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Alternative Name: Angiopoietin-1

Background: Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart.Synonyms: ANG-1, ANG1, ANGPT1, KIAA0003

Gene ID: 284

NCBI Accession: NP_001137

Pathways: RTK Signaling, Glycosaminoglycan Metabolic Process