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Asialoglycoprotein Receptor 1 antibody (N-Term)
ASGR1
Reactivity: Human
WB, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Asialoglycoprotein Receptor 1 Antibody
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Target
See all Asialoglycoprotein Receptor 1 (ASGR1) Antibodies
Asialoglycoprotein Receptor 1 (ASGR1)
Binding Specificity
All epitopes for Asialoglycoprotein Receptor 1 antibodies
AA 1-30, N-Term
Reactivity
All reactivities for Asialoglycoprotein Receptor 1 antibodies
Human
Host
All hosts for Asialoglycoprotein Receptor 1 antibodies
Rabbit
Clonality
All clonalities for Asialoglycoprotein Receptor 1 antibodies
Polyclonal
Conjugate
All conjugates for Asialoglycoprotein Receptor 1 antibodies
This Asialoglycoprotein Receptor 1 antibody is un-conjugated
Application
All applications for Asialoglycoprotein Receptor 1 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody reacts to ASGR1.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Affinity chromatography on Protein A
Immunogen
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human ASGR1
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) sodium azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Asialoglycoprotein Receptor 1
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Target
Asialoglycoprotein Receptor 1 (ASGR1)
Alternative Name
ASGR1 (ASGR1 Products )
Synonyms
ASGR1 antibody, ASGPR antibody, ASGPR1 antibody, CLEC4H1 antibody, HL-1 antibody, Asgr antibody, Asgr-1 antibody, ASGR antibody, RATRHL1 antibody, RHL1 antibody, asialoglycoprotein receptor 1 antibody, LOC721786 antibody, ASGR1 antibody, LOC489461 antibody, Asgr1 antibody, LOC101116157 antibody
Background
Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified.Synonyms: ASGP-R 1, ASGPR 1, Asialoglycoprotein receptor 1, Hepatic lectin H1
Gene ID
432
NCBI Accession
NP_001184145
Pathways
Thyroid Hormone Synthesis
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