ATL1 antibody (C-Term)

Catalog No. ABIN950554

This Rabbit Polyclonal antibody specifically detects ATL1 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for ATL1 antibody (C-Term) (ABIN950554)

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ATL1 Antibody

Binding Specificity: AA 476-504, C-Term

Specificity: This antibody reacts to Atlastin-1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human ATL1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ATL1

Target: ATL1 (Atlastin GTPase 1 (ATL1))

Alternative Name: Atlastin-1 / SPG3A

Background: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene.Synonyms: ATL1, Brain-specific GTP-binding protein, GBP-3, GBP3, GTP-binding protein 3, Guanine nucleotide-binding protein 3, Spastic paraplegia 3 protein A

Gene ID: 51062

NCBI Accession: NP_001121185