BHLHA15 antibody (C-Term)

Catalog No. ABIN950660

The Rabbit Polyclonal anti-BHLHA15 antibody is suitable to detect BHLHA15 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for BHLHA15 antibody (C-Term) (ABIN950660)

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHLHA15 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-BHLHA15 Antibody

Binding Specificity: AA 167-197, C-Term

Specificity: This antibody reacts to BHLHB8.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 167-197 amino acids from the C-terminal region of human BHLHA15

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BHLHA15

Target: BHLHA15 (Basic Helix-Loop-Helix Family, Member A15 (BHLHA15))

Alternative Name: BHLHB8 / BHLHA15

Background: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3' (By similarity).Synonyms: Class A basic helix-loop-helix protein 15, Class B basic helix-loop-helix protein 8, MIST1, Muscle, intestine and stomach expression 1

Gene ID: 168620

NCBI Accession: NP_803238