BPGM antibody (C-Term)

Catalog No. ABIN950665

This Rabbit Polyclonal antibody specifically detects BPGM in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for BPGM antibody (C-Term) (ABIN950665)

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BPGM antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-BPGM Antibody

Binding Specificity: AA 229-259, C-Term

Specificity: This antibody reacts to Bisphosphoglycerate mutase.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 229-259 amino acids from the C-terminal region of human BPGM

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BPGM

Target: BPGM (2,3-bisphosphoglycerate Mutase (BPGM))

Alternative Name: Bisphosphoglycerate Mutase

Background: 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.Synonyms: 2, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, BPG-dependent PGAM, BPGM, erythrocyte

Gene ID: 669

NCBI Accession: NP_001715