Calpain 3 antibody (C-Term)

Catalog No. ABIN951007

This Rabbit Polyclonal antibody specifically detects Calpain 3 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Calpain 3 antibody (C-Term) (ABIN951007)

Target: Calpain 3 (CAPN3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Calpain 3 Antibody

Binding Specificity: AA 610-640, C-Term

Specificity: This antibody reacts to CAPN3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 610~640 amino acids from the C-terminal region of human CAPN

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Calpain 3

Target: Calpain 3 (CAPN3)

Alternative Name: Calpain-3

Background: Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.Synonyms: CANP3, CANPL3, CAPN3, Calcium-activated neutral proteinase 3, Calpain L3, Calpain p94, Muscle-specific calcium-activated neutral protease 3, NCL1, New calpain 1

Molecular Weight: 94254 Da

Gene ID: 825

NCBI Accession: NP_000061

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development