CD94 antibody
Quick Overview for CD94 antibody (ABIN951438)
Target
See all CD94 (KLRD1) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Anti-mouse CD94 monoclonal antibody detects the mouse CD94 receptor.
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Purification
- Affinity chromatography on Protein G
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Immunogen
- Murine T cell clone AE7 cells Donor: Lewis Rat spleen cells Fusion Partner: Murine myeloma cell line SP2/0
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 1,0 mg/mL
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Buffer
- PBS containing 0.02 % sodium azide (NaN3) as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))
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Alternative Name
- CD94
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Background
- CD94 is a 180 amino acid, 70 KDa transmembrane glycoprotein that belongs to a family of murine Natural Killer (NK) cell receptors for MHC class I and is co-expressed as a heterodimer with NKG2 on the cellular surface. CD94 is expressed on NK cells as well as NK T cells. Both the murine CD94/NKG2 heterodimer and its human homologue are expressed on Th1 but not Th2 cells. Similar in function to the NKG2 family of receptors, CD94 is involved in NK target cell recognition, functions as an inhibitory receptor and plays an important role in adhesion and activation of the NK cell lineage. The unique expression of the CD94/NKG2 heterodimer on the Th1 subset of activated CD4+ cells suggests the potential use of our CL8950AP antibody in cell differentiation studies.Synonyms: KLRD1, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94
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Gene ID
- 16643
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NCBI Accession
- NP_034784
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UniProt
- O54707
Target
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