CENPH antibody (Middle Region)

Catalog No. ABIN951466

This Rabbit Polyclonal antibody specifically detects CENPH in WB, FACS, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for CENPH antibody (Middle Region) (ABIN951466)

Target: CENPH (Centromere Protein H (CENPH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CENPH antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-CENPH Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to CENPH.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CENPH

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CENPH

Target: CENPH (Centromere Protein H (CENPH))

Alternative Name: CENP-H

Background: Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.Synonyms: CENPH, Centromere protein H, ICEN35, Interphase centromere complex protein 35

Molecular Weight: 28481 Da

Gene ID: 64946

NCBI Accession: NP_075060