C12ORF29 antibody (N-Term)

Catalog No. ABIN951538

This Rabbit Polyclonal antibody specifically detects C12ORF29 in WB, FACS, IF, IHC (p) and EIA. It exhibits reactivity toward Human and Mouse.

Quick Overview for C12ORF29 antibody (N-Term) (ABIN951538)

Target: C12ORF29 (Chromosome 12 Open Reading Frame 29 (C12ORF29))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C12ORF29 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-C12ORF29 Antibody

Binding Specificity: AA 68-96, N-Term

Specificity: This antibody recognizes CL029 (N-term)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Peptide Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 68-96 amino acids from the N-terminal region of Human CL029 Genename: C12orf29

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for C12ORF29

Target: C12ORF29 (Chromosome 12 Open Reading Frame 29 (C12ORF29))

Alternative Name: C12orf29

Background: Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The C12orf29 gene product has been provisionally designated C12orf29 pending further characterization.

Molecular Weight: 37490 Da

Gene ID: 91298

NCBI Accession: NP_001009894