CLCNKB antibody (N-Term)

Catalog No. ABIN951557

The Rabbit Polyclonal anti-CLCNKB antibody is suitable to detect CLCNKB in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for CLCNKB antibody (N-Term) (ABIN951557)

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCNKB antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-CLCNKB Antibody

Binding Specificity: AA 10-40, N-Term

Specificity: This antibody reacts to CLCNKB.

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 10-40 amino acids from the N-terminal region of human CLCNKB

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLCNKB

Target: CLCNKB (Chloride Channel Kb (CLCNKB))

Alternative Name: CLCNKB

Background: The protein encoded by this gene is a member of the family of voltage-gated chloride channels. Chloride channels have several functions, including the regulation of cell volume, membrane potential stabilization, signal transduction and transepithelial transport. This gene is expressed predominantly in the kidney and may be important for renal salt reabsorption. Mutations in this gene are associated with autosomal recessive Bartter syndrome type 3 (BS3). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Synonyms: Chloride channel Kb, Chloride channel protein ClC-Kb, ClC-K2, ClCK2

Molecular Weight: 75446 Da

Gene ID: 1188

NCBI Accession: NP_000076