C3 antibody

Catalog No. ABIN951635

Product Details anti-C3 Antibody

Target: C3 (Complement Component 3 (C3))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This C3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Flow Cytometry (FACS)

Specificity: Reacts with Human Complement Component C3a.

Purification: Protein G Chromatography

Immunogen: Purified Human Complement Component 3a (C3a) peptide. Remarks: Donor: Chicken serum.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as a preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for C3

Target: C3 (Complement Component 3 (C3))

Alternative Name: Complement C3 (C3 Products)

Background: Complement Component C3a is a 9 KDa, 77 amino acid peptide, and is one of the cleavage products formed when C3 convertase splits C3 into C3a and C3b. C3 along with C1, C2 and C4 is involved in the initial stages of complement activation via the classical complement pathway. C3a is an anaphylatoxin along with C4a and C5a. C3a also allows for cellular chemotaxis.Synonyms: CPAMD1, Complement component 3

Gene ID: 718

NCBI Accession: NP_000055

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling