Coronin 1a antibody

Catalog No. ABIN951669

The Chicken Polyclonal anti-Coronin 1a antibody (ABIN951669) specifically detects Coronin 1a in IF and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for Coronin 1a antibody (ABIN951669)

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Reactivity: Human, Mouse

Host: Chicken

Clonality: Polyclonal

Conjugate: This Coronin 1a antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Coronin 1a Antibody

Specificity: Recognizes Coronin 1a.

Purification: Affinity Chromatography using a peptide column.

Immunogen: Synthetic peptide KLH conjugated corresponding to a sequence shared between the Mouse (NP_034028) and Human (NP_009005) gene products. After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted in the dark at 2-8 °C.

Target Details for Coronin 1a

Target: Coronin 1a (CORO1A) (Coronin, Actin Binding Protein, 1A (CORO1A))

Alternative Name: Coronin-1A

Background: Human Coronin 1a is a 51,026 dalton protein (461 amino acids) selectively expressed in cells involved in immune surveillance throughout the body, including activated microglial cells of the CNS. It is a member of the WD40 (tryptophan-aspartate) gene family, which includes the β subunit of the trimeric G proteins as the prototype. Its function is presumably in membrane structural reorganization accompanying antigenpresentation.Synonyms: CORO1, CORO1A, Clipin-A, Coronin-like protein, Coronin-like protein p57, TACO, Tryptophan aspartate-containing coat protein

Gene ID: 11151

NCBI Accession: NP_001180262

Pathways: Regulation of Actin Filament Polymerization