PPIF antibody (Middle Region)

Catalog No. ABIN951771

The Rabbit Polyclonal anti-PPIF antibody (ABIN951771) specifically detects PPIF in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for PPIF antibody (Middle Region) (ABIN951771)

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIF antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PPIF Antibody

Binding Specificity: AA 102-131, Middle Region

Specificity: This antibody recognizes Human Cyclophilin F (Center).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 102-131 amino acids from the Central region of Human Cyclophilin F. Genename: PPIF

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PPIF

Target: PPIF (Peptidylprolyl Isomerase F (PPIF))

Alternative Name: Cyclophilin F

Background: PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.Synonyms: CYP3, PPIF, PPIase F, Rotamase F, mitochondrial Peptidyl-prolyl cis-trans isomerase

Molecular Weight: 22040 Da

Gene ID: 10105

NCBI Accession: NP_005720

Pathways: Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity