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CYP1A2 antibody (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2) (AA 262-290) Primary Antibody

CYP1A2 Reactivity: Human, Mouse EIA, IF, IHC (p), WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN951775
$629.20
Plus shipping costs $45.00
0.4 mL
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Available
  • Target
    CYP1A2
    Binding Specificity
    • 16
    • 11
    • 10
    • 8
    • 7
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 262-290, Middle Region
    Reactivity
    • 75
    • 41
    • 26
    Human, Mouse
    Host
    • 58
    • 18
    • 8
    Rabbit
    Clonality
    • 69
    • 15
    Polyclonal
    Conjugate
    • 42
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CYP1A2 antibody is un-conjugated
    Application
    • 59
    • 43
    • 31
    • 22
    • 22
    • 13
    • 13
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Specificity
    This antibody recognizes Human and Mouse CYP1A2 (Center). Other species not tested.
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of Human CYP1A2. Genename: CYP1A2
    Isotype
    Ig Fraction
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CYP1A2
    Alternative Name
    CYP1A2 (CYP1A2 Antibody Abstract)
    Synonyms
    CP12, P3-450, P450(PA), CYP1A2, CYPIA2, P450-PM4, Cyp1a1, P450-3, CYPD45, P-450d, RATCYPD45, CYP1A5, CP450, CYP-IA2, cytochrome P450 family 1 subfamily A member 2, cytochrome P450 1A2, cytochrome P450 LM4, cytochrome P450, family 1, subfamily A, polypeptide 2, cytochrome P450, family 1, subfamily a, polypeptide 2, cytochrome P450 1A2-like, CYP1A2, LOC100328937, Cyp1a2, VDBG_06455, LOC101825565, LOC102130662
    Background
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.Synonyms: CYPIA2, Cytochrome P(3)450, Cytochrome P450 1A2, Cytochrome P450 4, Cytochrome P450-P3
    Molecular Weight
    58294 Da
    Gene ID
    1544
    NCBI Accession
    NP_000752
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