Cytohesin 4 antibody (C-Term)
Quick Overview for Cytohesin 4 antibody (C-Term) (ABIN951805)
Target
See all Cytohesin 4 (CYTH4) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 290-319, C-Term
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Specificity
- This antibody recognizes Human Cytohesin-4 (C-term).
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Purification
- Affinity Chromatography on Protein A
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Immunogen
- KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of Human CYTH4 Genename: CYTH4
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Cytohesin 4 (CYTH4)
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Alternative Name
- Cytohesin 4
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Background
- The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The structures of this gene and CYTH1 are very similar. [provided by RefSeq].Synonyms: CYT4, CYTH4, PSCD4
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Molecular Weight
- 45672 Da
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Gene ID
- 27128
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NCBI Accession
- NP_037517
Target
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