Cytokeratin 1 antibody (Middle Region)

Catalog No. ABIN951809

The Rabbit Polyclonal anti-Cytokeratin 1 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect Cytokeratin 1 in samples from Human.

Quick Overview for Cytokeratin 1 antibody (Middle Region) (ABIN951809)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytokeratin 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Cytokeratin 1 Antibody

Binding Specificity: AA 422-451, Middle Region

Specificity: This antibody reacts to KRT1.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide between 422~451 amino acids from the Central region of human KRT1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Alternative Name: Cytokeratin 1

Background: KRT1 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.Synonyms: 67 kDA cytokeratin, Cytokeratin 1, Hair alpha protein, K1, KRT1, KRTA, Keratin type II cytoskeletal 1, Keratin-1

Molecular Weight: 66039 Da

Gene ID: 3848

NCBI Accession: NP_006112