Keratin 3 antibody (Middle Region)

Catalog No. ABIN951817

This Rabbit Polyclonal antibody specifically detects Keratin 3 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for Keratin 3 antibody (Middle Region) (ABIN951817)

Target: Keratin 3 (KRT3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Keratin 3 Antibody

Binding Specificity: AA 413-441, Middle Region

Specificity: This antibody reacts to KRT3.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 413-441 amino acids from the Central region of human KRT3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Keratin 3

Target: Keratin 3 (KRT3)

Alternative Name: Cytokeratin 3

Background: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.Synonyms: 65 kDa cytokeratin, KRT3, Keartin-3, Keratin, Type-II keratin Kb3, type II cytoskeletal 3

Molecular Weight: 64417 Da

Gene ID: 3850

NCBI Accession: NP_476429