DAZ3 antibody (C-Term)

Catalog No. ABIN951839

The Rabbit Polyclonal anti-DAZ3 antibody is suitable to detect DAZ3 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for DAZ3 antibody (C-Term) (ABIN951839)

Target: DAZ3 (Deleted In Azoospermia 3 (DAZ3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-DAZ3 Antibody

Binding Specificity: AA 396-426, C-Term

Specificity: This antibody recognizes Human DAZ3 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 396-426 amino acids from the C-terminal region of Human DAZ3. Genename: DAZ3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DAZ3

Target: DAZ3 (Deleted In Azoospermia 3 (DAZ3))

Alternative Name: DAZ3

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.Synonyms: Deleted in azoospermia protein 3

Molecular Weight: 54989 Da

Gene ID: 57054

NCBI Accession: NP_065097