DIAPH3 antibody (C-Term)

Catalog No. ABIN951910

Product Details anti-DIAPH3 Antibody

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Binding Specificity: AA 1060-1090, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DIAPH3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human DIAPH3 (C-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 1060-1090 amino acids from the C-terminal region of human DIAPH3.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DIAPH3

Target: DIAPH3 (Diaphanous Homolog 3 (Drosophila) (DIAPH3))

Alternative Name: DIAPH3 (DIAPH3 Products)

Background: DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).Synonyms: DIAP3, DRF3, Diaphanous homolog 3, Diaphanous-3, Diaphanous-related formin-3

Molecular Weight: 136926 Da

Gene ID: 81624

NCBI Accession: NP_001035982