DKK1 antibody (N-Term)

Catalog No. ABIN951911

The Rabbit Polyclonal anti-DKK1 antibody is suitable to detect DKK1 in samples from Human. It has been validated for WB and EIA.

Quick Overview for DKK1 antibody (N-Term) (ABIN951911)

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DKK1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-DKK1 Antibody

Binding Specificity: AA 64-93, N-Term

Specificity: This antibody recognizes Human Dickkopf-1 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 64~93 amino acids from the N-terminal region of Human Dickkopf-1. Genename: DKK1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for DKK1

Target: DKK1 (Dickkopf Homolog 1 (DKK1))

Alternative Name: Dickkopf-1

Background: DKK1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.Synonyms: DKK-1, DKK1, Dickkopf-related protein 1, SK

Molecular Weight: 28672 Da

Gene ID: 22943

NCBI Accession: NP_036374

Pathways: WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation