EMILIN2 antibody

Catalog No. ABIN952078

This Rat Monoclonal antibody specifically detects EMILIN2 in WB, IP and FACS. It exhibits reactivity toward Human.

Quick Overview for EMILIN2 antibody (ABIN952078)

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This EMILIN2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS)

Clone: 828B3B3

Product Details anti-EMILIN2 Antibody

Specificity: This antibody was selected for its ability to detect Human Emilin-2.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G

Immunogen: Recombinant protein gC1q domain of EMILIN-2.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Centrifuge vial prior to opening. Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Buffer: PBS

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for at least 6 months.

Expiry Date: 6 months

Target Details for EMILIN2

Target: EMILIN2 (Elastin Microfibril Interfacer 2 (EMILIN2))

Alternative Name: EMILIN2

Background: Emilins (elastin microfibril interface located proteins) are extracellular matrix glycoproteins that localize to sites with proximity to elastin and microfibrils. They consist of an N-terminal cysteine-rich EMI domain and a conserved C-terminal gC1q-like domain. Emilin-1 is abundant in elastin-rich tissues such as blood vessels, skin, heart and lung. It influences placenta formation and initial organogenesis with a later role in interstitial connective tissue. Emilin-2 is larger than Emilin-1 and contains a unique proline-rich domain. It is likely involved in the process of elastogenesis. Multimerin-2 (also known as Emilin-3 or EndoGlyx-1) is expressed during embryonic development. Multimerin-1 (also known as Emilin-4) is expressed in platelets and the endothelium of blood vessels and may act as a carrier protein for platelet factor V. Emilin-5 is encoded by the Emilin-3 gene and is sometimes referred to as Emilin-3. It contains the N-terminal cysteine-rich EMI domain but lacks the C-terminal gC1q-like domain. Emilin-5 is expressed in human mesenchymal stem cells and plays an important role in skeletal development.Synonyms: EMILIN-2, Elastin microfibril interface-located protein 2, Elastin microfibril interfacer 2, Protein FOAP-10

Gene ID: 84034

NCBI Accession: NP_114437

UniProt: Q9BXX0