Endothelin 1 antibody (C-Term)

Catalog No. ABIN952084

This Rabbit Polyclonal antibody specifically detects Endothelin 1 in WB, IF, IHC (p), EIA. It exhibits reactivity toward Human.

Quick Overview for Endothelin 1 antibody (C-Term) (ABIN952084)

Target: Endothelin 1 (EDN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Endothelin 1 Antibody

Binding Specificity: AA 183-211, C-Term

Specificity: This antibody recognizes Human Endothelin-1 (C-term). Other species not tested.

Purification: Affinity Chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 183-211 amino acids from the C-terminal region of human EDN1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Endothelin 1

Target: Endothelin 1 (EDN1)

Alternative Name: Endothelin-1

Background: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: EDN1, ET1, HDLCQ7, PPET1, Preproendothelin-1

Molecular Weight: 24425 Da

Gene ID: 1906

NCBI Accession: NP_001161791

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size