Endothelin 1 antibody (AA 113-212)

Catalog No. ABIN560688

Cited in 3+ publications. The Mouse Monoclonal anti-Endothelin 1 antibody (Clone 3D6) (ABIN560688) specifically detects Endothelin 1 in WB, IP and ELISA. The antibody is reactive with Human samples.

Quick Overview for Endothelin 1 antibody (AA 113-212) (ABIN560688)

Target: Endothelin 1 (EDN1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Endothelin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA

Clone: 3D6

Product Details anti-Endothelin 1 Antibody

Binding Specificity: AA 113-212

Purpose: Mouse monoclonal antibody raised against a partial recombinant EDN1.

Sequence: SQKDKKCWNF CQAGKELRAE DIMEKDWNNH KKGKDCSKLG KKCIYQQLVR GRKIRRSSEE HLRQTRSETM RNSVKSSFHD PKLKGNPSRE RYVTHNRAHW

Cross-Reactivity: Human

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: EDN1 (AAH09720, 113 a.a. ~ 212 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-Endothelin 1 antibody (ABIN560688)

Marion, Dieudonné, Patiño-Garcia, Lecanda, Marie, Modrowski: "Calpain-6 is an endothelin-1 signaling dependent protective factor in chemoresistant osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 130, Issue 11, pp. 2514-25, (2012) (PubMed).

Schildroth, Rettig-Zimmermann, Kalk, Steege, Fähling, Sendeski, Paliege, Lai, Bachmann, Persson, Hocher, Patzak: "Endothelin type A and B receptors in the control of afferent and efferent arterioles in mice." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 26, Issue 3, pp. 779-89, (2011) (PubMed).

Ghoul, Serova, Astorgues-Xerri, Bieche, Bousquet, Varna, Vidaud, Phillips, Weill, Benhadji, Lokiec, Cvitkovic, Faivre, Raymond: "Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells." in: Cancer research, Vol. 69, Issue 10, pp. 4260-9, (2009) (PubMed).

Target Details for Endothelin 1

Target: Endothelin 1 (EDN1)

Alternative Name: EDN1

Background: Full Gene Name: endothelin 1
Synonyms: ET1,HDLCQ7

Gene ID: 1906

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size