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FBXO4 antibody (Middle Region)

FBXO4 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN952288
  • Target See all FBXO4 Antibodies
    FBXO4 (F-Box Protein 4 (FBXO4))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    AA 231-260, Middle Region
    Reactivity
    • 47
    • 19
    • 19
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Host
    • 41
    • 4
    • 2
    Rabbit
    Clonality
    • 45
    • 2
    Polyclonal
    Conjugate
    • 20
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FBXO4 antibody is un-conjugated
    Application
    • 39
    • 21
    • 13
    • 4
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Human FBXO4 (Center).
    Purification
    Affinity Chromatography on Protein A
    Immunogen
    KLH conjugated synthetic peptide between 231~260 amino acids from the Center region of human FBXO4
    Isotype
    Ig Fraction
    Top Product
    Discover our top product FBXO4 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS containing 0.09 % (W/V) Sodium Azide as preservative
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Barbash, Zamfirova, Lin, Chen, Yang, Nakagawa, Lu, Rustgi, Diehl: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." in: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).

  • Target
    FBXO4 (F-Box Protein 4 (FBXO4))
    Alternative Name
    FBXO4 (FBXO4 Products)
    Synonyms
    FBX4 antibody, 1700096C12Rik antibody, AI851261 antibody, AW494535 antibody, Fbx4 antibody, FBXO4 antibody, fbx4 antibody, si:dkey-46a10.2 antibody, F-box protein 4 antibody, F-box protein 4 L homeolog antibody, FBXO4 antibody, Fbxo4 antibody, fbxo4 antibody, fbxo4.L antibody
    Background
    FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.Synonyms: F-box only protein 4, FBX4
    Molecular Weight
    44136 Da
    Gene ID
    26272
    NCBI Accession
    NP_036308
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