FEZF1 antibody (N-Term)

Catalog No. ABIN952301

The Rabbit Polyclonal anti-FEZF1 antibody is suitable to detect FEZF1 in samples from Human and Mouse. It has been validated for WB and EIA.

Quick Overview for FEZF1 antibody (N-Term) (ABIN952301)

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEZF1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-FEZF1 Antibody

Binding Specificity: AA 67-96, N-Term

Specificity: This antibody reacts to FEZF1.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human FEZF1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FEZF1

Target: FEZF1 (FEZ Family Zinc Finger 1 (FEZF1))

Alternative Name: FEZF1

Background: Transcription repressor. Involved in the axonal projection and proper termination of olfactory sensory neurons (OSN). Plays a role in rostro-caudal patterning of the diencephalon and in prethalamic formation. Expression is required in OSN to cell-autonomously regulate OSN axon projections. Regulates non-cell-autonomously the layer formation of the olfactory bulb development and the interneurons. May be required for correct rostral migration of the interneuron progenitors. FEZF1 is expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2-to 20-fold increase is found in over 50 % of gastric cancer tissues. Subcellular location of FEZF1 is in the nucleus.Synonyms: FEZ, Fez family zinc finger protein 1, ZNF312B, Zinc finger protein 312B

Molecular Weight: 52038 Da

Gene ID: 389549

NCBI Accession: NP_001019784