FUS antibody (C-Term)

Catalog No. ABIN952406

The Rabbit Polyclonal anti-FUS antibody has been validated for WB, IF, IHC (p), FACS and EIA. It is suitable to detect FUS in samples from Human and Mouse.

Quick Overview for FUS antibody (C-Term) (ABIN952406)

Target: FUS (Fused in Sarcoma (FUS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUS antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Product Details anti-FUS Antibody

Binding Specificity: AA 506-534, C-Term

Specificity: This antibody recognizes Human and Mouse FUS (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 506-534 amino acids from the C-terminal region of human FUS

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for FUS

Target: FUS (Fused in Sarcoma (FUS))

Alternative Name: FUS / TLS

Background: This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.Synonyms: 75 kDa DNA-pairing protein, Oncogene FUS, Oncogene TLS, POMp75, RNA-binding protein FUS, Translocated in liposarcoma protein

Molecular Weight: 53426 Da

Gene ID: 2521

NCBI Accession: NP_001164105