GAB3 antibody (N-Term)

Catalog No. ABIN952418

The Rabbit Polyclonal anti-GAB3 antibody is suitable to detect GAB3 in samples from Human. It has been validated for WB and EIA.

Quick Overview for GAB3 antibody (N-Term) (ABIN952418)

Target: GAB3 (GRB2-Associated Binding Protein 3 (GAB3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAB3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-GAB3 Antibody

Binding Specificity: AA 29-58, N-Term

Specificity: This antibody recognizes Human GAB3 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of Human GAB3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GAB3

Target: GAB3 (GRB2-Associated Binding Protein 3 (GAB3))

Alternative Name: GAB3

Background: GAB3 is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: GRB2-associated binder 3, GRB2-associated-binding protein 3, Growth factor receptor bound protein 2-associated protein 3

Molecular Weight: 65589 Da

Gene ID: 139716

NCBI Accession: NP_001075042