Gephyrin antibody (Middle Region)

Catalog No. ABIN952493

The Rabbit Polyclonal anti-Gephyrin antibody has been validated for WB, FACS and IHC (p). It is suitable to detect Gephyrin in samples from Human and Mouse.

Quick Overview for Gephyrin antibody (Middle Region) (ABIN952493)

Target: Gephyrin (GPHN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Gephyrin Antibody

Binding Specificity: AA 444-474, Middle Region

Specificity: This antibody reacts to GPHN.

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 444~474 amino acids from the Central region of human GPHN

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: Gephyrin

Background: GPHN encodes a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the encoded protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency.Synonyms: GPH, GPHN, KIAA1385

Molecular Weight: 79748 Da

Gene ID: 10243

NCBI Accession: NP_001019389

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development