GSTA3 antibody (N-Term)

Catalog No. ABIN952641

The Rabbit Polyclonal anti-GSTA3 antibody (ABIN952641) specifically detects GSTA3 in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for GSTA3 antibody (N-Term) (ABIN952641)

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSTA3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-GSTA3 Antibody

Binding Specificity: AA 1-30, N-Term

Specificity: This antibody recognizes Human GSTA3 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GSTA3.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GSTA3

Target: GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))

Alternative Name: GSTA3

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.Synonyms: GST class-alpha member 3, Glutathione S-transferase A3-3

Molecular Weight: 25302 Da

Gene ID: 2940

NCBI Accession: NP_000838