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HFE2 antibody (Middle Region)
HFE2
Reactivity: Human, Mouse
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-HFE2 Antibody
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Target
See all HFE2 Antibodies
HFE2
(Hemochromatosis Type 2 (Juvenile) (HFE2))
Binding Specificity
All epitopes for HFE2 antibodies
AA 141-170, Middle Region
Reactivity
All reactivities for HFE2 antibodies
Human, Mouse
Host
All hosts for HFE2 antibodies
Rabbit
Clonality
All clonalities for HFE2 antibodies
Polyclonal
Conjugate
All conjugates for HFE2 antibodies
This HFE2 antibody is un-conjugated
Application
All applications for HFE2 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody recognizes Human and Mouse HFE2 / Hemojuvelin (Center).
Purification
Protein A column, followed by peptide affinity purification
Immunogen
KLH conjugated synthetic peptide between 141~170 amino acids from the Central region of Human HFE2 / Hemojuvelin
Isotype
Ig Fraction
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Discover our top product HFE2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for HFE2
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Target
HFE2
(Hemochromatosis Type 2 (Juvenile) (HFE2))
Alternative Name
HFE2 / Hemojuvelin (HFE2 Products )
Synonyms
HFE2A antibody, HJV antibody, JH antibody, RGMC antibody, HFE2 antibody, DKFZp468F2322 antibody, 2310035L15Rik antibody, 5230400G09Rik antibody, AI414844 antibody, AI789733 antibody, DL-M antibody, Rgmc antibody, hemojuvelin antibody, RGMr antibody, hjv antibody, id:ibd3464 antibody, wu:fb38f10 antibody, zgc:136698 antibody, hemochromatosis type 2 (juvenile) antibody, hemochromatosis type 2 antibody, HFE2 antibody, Hfe2 antibody, hfe2 antibody
Background
HFE2 is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin.Synonyms: HJV, Hemochromatosis type 2 protein, RGM domain family member C, RGMC
Molecular Weight
45080 Da
Gene ID
148738
NCBI Accession
NP_660320
Pathways
Transition Metal Ion Homeostasis
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