HMGCL antibody (Middle Region)

Catalog No. ABIN952759

This Rabbit Polyclonal antibody specifically detects HMGCL in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for HMGCL antibody (Middle Region) (ABIN952759)

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGCL antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-HMGCL Antibody

Binding Specificity: AA 160-190, Middle Region

Specificity: This antibody recognizes Human HMG-CoA lyase / HMGCL (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 160-190 amino acids from the Central region of human HMG-CoA lyase / HMGCL

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for HMGCL

Target: HMGCL (3-Hydroxymethyl-3-Methylglutaryl-CoA Lyase (HMGCL))

Alternative Name: HMG-CoA Lyase / HMGCL

Background: HMGCL belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].Synonyms: mitochondrial Hydroxymethylglutaryl-CoA lyase

Molecular Weight: 34360 Da

Gene ID: 3155

NCBI Accession: NP_000182