Indian Hedgehog antibody (N-Term)
Quick Overview for Indian Hedgehog antibody (N-Term) (ABIN952896)
Target
See all Indian Hedgehog (IHH) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 50-80, N-Term
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Specificity
- This antibody detects Indian hedgehog protein / IHH.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 50-80aa) of human Indian hedgehog protein / IHH.
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Indian Hedgehog (IHH)
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Alternative Name
- Indian Hedgehog Protein / IHH
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Background
- The IHH gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia.Synonyms: HHG-2, HHG2
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Gene ID
- 3549
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NCBI Accession
- NP_002172
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Pathways
- Hedgehog Signaling
Target
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