MED6 antibody (Middle Region)

Catalog No. ABIN953376

This anti-MED6 antibody is a Rabbit Polyclonal antibody detecting MED6 in WB and EIA. Suitable for Human.

Quick Overview for MED6 antibody (Middle Region) (ABIN953376)

Target: MED6 (Mediator Complex Subunit 6 (MED6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MED6 Antibody

Binding Specificity: AA 134-164, Middle Region

Specificity: This antibody recognizes Human MED6 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 134-164 amino acids from the Central region of human MED6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MED6

Target: MED6 (Mediator Complex Subunit 6 (MED6))

Alternative Name: MED6

Background: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Synonyms: ARC33, Activator-recruited cofactor 33 kDa component, Mediator complex 6, Mediator of RNA polymerase II transcription subunit 6, Renal carcinoma antigen NY-REN-28

Molecular Weight: 28425 Da

Gene ID: 10001

NCBI Accession: NP_005457

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha