MESDC2 antibody (C-Term)

Catalog No. ABIN953390

The Rabbit Polyclonal anti-MESDC2 antibody has been validated for WB, IF and EIA. It is suitable to detect MESDC2 in samples from Human.

Quick Overview for MESDC2 antibody (C-Term) (ABIN953390)

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MESDC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Product Details anti-MESDC2 Antibody

Binding Specificity: AA 203-234, C-Term

Specificity: This antibody reacts to MESDC2.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogen: KLH conjugated synthetic peptide between 203-234 amino acids from the C-terminal region of human MESDC2

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MESDC2

Target: MESDC2 (Mesoderm Development Candidate 2 (MESDC2))

Alternative Name: MESDC2

Background: Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.Synonyms: KIAA0081, MESDC2, Mesoderm development candidate 2, UNQ1911/PRO4369

Molecular Weight: 26077 Da

Gene ID: 23184

NCBI Accession: NP_055969