MYLK antibody (Middle Region)

Catalog No. ABIN953458

This Rabbit Polyclonal antibody specifically detects MYLK in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for MYLK antibody (Middle Region) (ABIN953458)

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYLK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MYLK Antibody

Binding Specificity: AA 542-570, Middle Region

Specificity: This antibody recognizes human MYLK / MYLK3.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the central region (between 542-570aa) of human MLCK / MYLK3

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MYLK

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Alternative Name: MLCK

Background: Phosphorylation of cardiac myosin heavy chains (like MYH7B) and light chains (like MYL2) by a kinase, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocytes [Chan et al., 2008, PubMed 18202317].Synonyms: MYLK3, Putative myosin light chain kinase 3

Molecular Weight: 88393 Da

Gene ID: 91807

NCBI Accession: NP_872299