MTMR6 antibody (N-Term)

Catalog No. ABIN953537

The Rabbit Polyclonal anti-MTMR6 antibody is suitable to detect MTMR6 in samples from Human. It has been validated for WB and EIA.

Quick Overview for MTMR6 antibody (N-Term) (ABIN953537)

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTMR6 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MTMR6 Antibody

Binding Specificity: AA 113-143, N-Term

Specificity: This antibody recognizes human MTMR6 at N-term.

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 113-143aa) of human MTMR6

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for MTMR6

Target: MTMR6 (Myotubularin Related Protein 6 (MTMR6))

Alternative Name: MTMR6

Background: Myotubularin-related protein 6 is a phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase and negatively regulates proliferation of reactivated CD4+ T-cellsMyotubularin-related protein 6Synonyms: Myotubularin-related protein 6

Molecular Weight: 71954 Da

Gene ID: 9107

NCBI Accession: NP_004676

Pathways: Inositol Metabolic Process