MXI1 antibody (MAX Interactor 1) (AA 52-82)

Details for Product anti-MXI1 Antibody No. ABIN953554
Target
Binding Specificity
AA 52-82, Middle Region
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1
Reactivity
Human, Mouse
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34
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6
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2
2
2
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2
1
Host
Rabbit
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7
3
Clonality
Polyclonal
Conjugate
This MXI1 antibody is un-conjugated
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3
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1
1
1
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1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
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26
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1
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Options
Immunogen Synthetic peptide - KLH conjugated - corresponding to the central region (between 52-82aa) of human MXI1.
Isotype Ig Fraction
Specificity This antibody recognizes human and mouse MXI1.
Purification Purified through a Protein A column followed by peptide affinity purification
Target
Alternative Name MXI1 (MXI1 Antibody Abstract)
Background Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.Synonyms: Class C basic helix-loop-helix protein 11, MAX-interacting protein 1, Max interactor 1, bHLHc11
Molecular Weight 26062 Da
Gene ID 4601
NCBI Accession NP_005953
Pathways Maintenance of Protein Location
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Images
Image no. 1 for anti-MAX Interactor 1 (MXI1) (AA 52-82), (Middle Region) antibody (ABIN953554) Western blot analysis in mouse heart tissue lysates (35ug/lane) using MXI1 Antibody ....