ENO2/NSE antibody

Catalog No. ABIN953674

This Mouse Monoclonal antibody specifically detects ENO2/NSE in WB, IHC (fro) and EIA. It exhibits reactivity toward Human.

Quick Overview for ENO2/NSE antibody (ABIN953674)

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ENO2/NSE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Clone: NSE-P2

Product Details anti-ENO2/NSE Antibody

Specificity: This antibody recognizes Neuron-Specific Enolase (NSE, ENO2).

Purification: Protein G Chromatography.

Immunogen: Enolase of Human origin.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ENO2/NSE

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Alternative Name: Neuron Specific Enolase

Background: Neuron-specific enolase 2 (NSE-P2, ENO2, Enolase 2, 2-Phospho-D-Glycerate Hydrolase, gamma neuronal, gamma/gamma) is an 80 kD protein and one of the five isozymes of enolase, a glycolytic enzyme catalyzing the reaction pathway between 2 phospho glycerate and phosphoenol pyruvate. Enolase is thought to serve as a growth factor in neurons and is released into the central nervous system when neural tissue is injured. Measurement of NSE levels in patients with neuroblastoma and small lung cancer can give an indication as to the extent of the disease. NSE-P2 is one of three different enolase isozymes found in the human brain.Synonyms: 2-phospho-D-glycerate hydro-lyase, ENO2, Enolase 2, Gamma-enolase, NSE, Neural enolase

Gene ID: 2026

NCBI Accession: NP_001966

UniProt: P09104