NKAP antibody (C-Term)
Quick Overview for NKAP antibody (C-Term) (ABIN953710)
Target
See all NKAP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 394-415, C-Term
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Specificity
- This antibody recognizes human NKAP at C-term.
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 394-415aa) of human NKAP
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NKAP (NFKB Activating Protein (NKAP))
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Alternative Name
- NKAP
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Background
- The NKAP gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6.Synonyms: NF-kappa-B-activating protein
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Molecular Weight
- 47138 Da
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Gene ID
- 79576
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NCBI Accession
- NP_078804
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Pathways
- Stem Cell Maintenance, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
Target
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