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Osteopontin antibody (N-Term)

The Rabbit Polyclonal anti-Osteopontin antibody has been validated for WB, IHC (p), IF and EIA. It is suitable to detect Osteopontin in samples from Human.
Catalog No. ABIN953945

Quick Overview for Osteopontin antibody (N-Term) (ABIN953945)

Target

See all Osteopontin (SPP1) Antibodies
Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Reactivity

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Human

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This Osteopontin antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • Binding Specificity

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    AA 21-48, N-Term

    Specificity

    This antibody recognizes Human Osteopontin (OPN-a/b) (N-term).

    Purification

    Protein A column, followed by peptide affinity purification

    Immunogen

    KLH conjugated synthetic peptide between 21-48 amino acids from the N-terminal region of Human Osteopontin (OPN-a/b) Genename: SPP1

    Isotype

    Ig Fraction
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS containing 0.09 % (W/V) Sodium Azide as preservative

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

    Alternative Name

    Osteopontin / SPP1

    Background

    Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity (By similarity).Synonyms: BNSP, Bone Sialoprotein 1, Nephropontin, OPN, SPP-1, Secreted Phosphoprotein 1, Urinary Stone Protein, Uropontin

    Molecular Weight

    35423 Da

    Gene ID

    6696

    NCBI Accession

    NP_000573

    Pathways

    Regulation of Cell Size
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