PCDHB12 antibody (C-Term)

Catalog No. ABIN954041

The Rabbit Polyclonal anti-PCDHB12 antibody is suitable to detect PCDHB12 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for PCDHB12 antibody (C-Term) (ABIN954041)

Target: PCDHB12 (Protocadherin beta 12 (PCDHB12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-PCDHB12 Antibody

Binding Specificity: AA 765-795, C-Term

Specificity: This antibody detects human PCDHB12 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a protein A column; followed by peptide affinity purification.

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 765-795aa) of human PCDHB12.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHB12

Target: PCDHB12 (Protocadherin beta 12 (PCDHB12))

Alternative Name: PCDHB12

Background: The PCDHB12 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-12, Protocadherin beta-12

Gene ID: 56124

NCBI Accession: NP_061755