PCDHB13 antibody (Middle Region)
Quick Overview for PCDHB13 antibody (Middle Region) (ABIN954042)
Target
See all PCDHB13 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 280-308, Middle Region
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Specificity
- This antibody recognizes PCDHB13.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogen
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 280-308aa) of human PCDHB13.
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PCDHB13 (Protocadherin beta 13 (PCDHB13))
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Alternative Name
- PCDHB13
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Background
- The PCDHB13 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-13, Protocadherin beta-13
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Gene ID
- 56123
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NCBI Accession
- NP_061756
Target
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