PCDHB15 antibody (N-Term)

Catalog No. ABIN954044

The Rabbit Polyclonal anti-PCDHB15 antibody is suitable to detect PCDHB15 in samples from Human. It has been validated for WB and EIA.

Quick Overview for PCDHB15 antibody (N-Term) (ABIN954044)

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHB15 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PCDHB15 Antibody

Binding Specificity: AA 120-148, N-Term

Specificity: This antibody recognizes PCDHB15 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the N-terminal region (between 120-148aa) from of human PCDHB15.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PCDHB15

Target: PCDHB15 (Protocadherin beta 15 (PCDHB15))

Alternative Name: PCDHB15

Background: The PCDHB15 gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.Synonyms: PCDH-beta-15, Protocadherin beta-15

Gene ID: 56121

NCBI Accession: NP_061758