PEX14 antibody (Middle Region)
Quick Overview for PEX14 antibody (Middle Region) (ABIN954097)
Target
See all PEX14 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-150, Middle Region
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Specificity
- This antibody recognizes Human and Mouse Peroxin 14 / PEX14 (Center).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogen
- KLH conjugated synthetic peptide between 120-150 amino acids from the Central region of Human Peroxin 14 / PEX14
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Isotype
- Ig Fraction
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PEX14 (Peroxisomal Biogenesis Factor 14 (PEX14))
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Alternative Name
- Peroxin 14 / PEX14
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Background
- This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.Synonyms: PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane protein PEX14
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Molecular Weight
- 41237 Da
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Gene ID
- 5195
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NCBI Accession
- NP_004556
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Pathways
- Maintenance of Protein Location
Target
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