Phospholamban antibody (Thr17)
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- Target See all Phospholamban (PLN) Antibodies
- Phospholamban (PLN)
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Binding Specificity
- Thr17
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Phospholamban antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Specificity
- This antibody recognizes Human Phospholamban (Thr17).
- Purification
- Protein A column, followed by peptide affinity purification
- Immunogen
- KLH conjugated synthetic peptide selected from the Thr17 region of Human Phospholamban Genename: PLN
- Isotype
- Ig Fraction
- Top Product
- Discover our top product PLN Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Phospholamban (PLN)
- Alternative Name
- Phospholamban (PLN Products)
- Background
- PLB is a 52 amino acid phosphoprotein which regulates the calcium pump of cardiac sarcoplasmic reticulum (SR). PLB is an oligomer of five identical subunits each having a cytoplasmic and transmembrane domain. The cytoplasmic domain (residues 1 to 25) contains the phosphorylation sites and is highly basic and readily cleaved by proteases, whereas the transmembrane domain (residues 25 to 52) is mostly hydrophobic, protease resistant and stabilizes the pentamer.Synonyms: Cardiac phospholamban, PLB, PLN
- Molecular Weight
- 6109 Da
- Gene ID
- 5350
- NCBI Accession
- NP_002658
- Pathways
- Negative Regulation of Transporter Activity
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