PJA1 antibody (N-Term)

Catalog No. ABIN954154

Product Details anti-PJA1 Antibody

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Binding Specificity: AA 154-183, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PJA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human PJA1 / RNF70 (N-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human PJA / RNF70

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PJA1

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Alternative Name: PJA1 / RNF70 (PJA1 Products)

Synonyms: PRAJA1 antibody, RNF70 antibody, praja ring finger ubiquitin ligase 1 antibody, PJA1 antibody, Pja1 antibody

Background: This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants.Synonyms: E3 ubiquitin-protein ligase Praja-1, Praja-1, Praja1, RING finger protein 70

Molecular Weight: 71002 Da

Gene ID: 64219

NCBI Accession: NP_071763