PLA2G5 antibody (C-Term)

Catalog No. ABIN954163

This Rabbit Polyclonal antibody specifically detects PLA2G5 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for PLA2G5 antibody (C-Term) (ABIN954163)

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G5 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PLA2G5 Antibody

Binding Specificity: AA 102-132, C-Term

Specificity: This antibody recognizes PLA2G5 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogen: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 102-132aa) of human PLA2G5.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PLA2G5

Target: PLA2G5 (phospholipase A2, Group V (PLA2G5))

Alternative Name: PLA2G5

Background: The PLA2G5 gene is a member of the secretory phospholipase A2 family. It is located in a tightly-linked cluster of secretory phospholipase A2 genes on chromosome 1. The encoded enzyme catalyzes the hydrolysis of membrane phospholipids to generate lysophospholipids and free fatty acids including arachidonic acid. It preferentially hydrolyzes linoleoyl-containing phosphatidylcholine substrates. Secretion of this enzyme is thought to induce inflammatory responses in neighboring cells. Alternatively spliced transcript variants have been found, but their full-length nature has not been determined.Synonyms: Calcium-dependent phospholipase A2, Group V phospholipase A2, PLA2-10, Phosphatidylcholine 2-acylhydrolase

Gene ID: 5322

NCBI Accession: NP_000920

Pathways: Inositol Metabolic Process